I don't know why, but I really liked this one particular quote:
"Nobody's really happy. We have good days, we have bad days, we have really really good days, and really really bad days, but that's what makes life interesting."
Oh and from the commercial they played a good 3 dozen times while I was watching the show:
WRT Success:
"You have to be willing to make a complete and total ass of yourself." - Johnny Depp